SPATIAL ORIENTATION GROUP

The team is working on spa­tial ori­en­ta­tion, a sys­tem-lev­el top­ic, by study­ing its under­ly­ing func­tion­al and struc­tur­al deter­mi­nants in ani­mals, as well as by ana­lyz­ing human behav­ior on earth and in space. We rely on a wide range of exper­i­men­tal approach­es, and we care­ful­ly tie togeth­er dif­fer­ent lev­els of inves­ti­ga­tion in an over­arch­ing frame­work. This mul­ti-lay­ered approach and com­bi­na­tion of exper­tise ded­i­cat­ed to func­tion­al stud­ies con­sti­tute the team’s uniqueness at both the nation­al and inter­na­tion­al lev­el.
Basic under­stand­ing gained in exper­i­ments per­formed both on ground and in weight­less­ness will be applied to bet­ter diag­nose and treat dis­eases, and con­verse­ly, patho­log­i­cal dys­func­tion may allow new insight into healthy brain func­tion.
Our work is sup­port­ed by the French spa­tial agency (CNES), ANR, CNRS & Uni­ver­sité Paris Descartes.

Research topics
  • Theme 1 : Mul­ti­sen­so­ry inte­gra­tion, Ori­en­ta­tion and Spa­tial Per­cep­tion
    – Visuo-hap­tic inte­gra­tion and spa­tial per­cep­tion.
    – Visuo-vestibu­lar inter­ac­tions for spa­tial ori­en­ta­tion.
    – Influ­ence of grav­i­ty on mul­ti­sen­so­ry inte­gra­tion: weight­less­ness and hyper­grav­i­ty exper­i­ments.
  • Theme 2 : Cor­ti­cal and sub­cor­ti­cal cir­cuits for spa­tial ori­en­ta­tion
    – Role of inhi­bi­tion in the thal­a­mo-pre­subic­u­lar pro­cess­ing of head direc­tion sig­nals.
    – Head direc­tion cir­cuit archi­tec­ture and spe­cif­ic role of neu­ronal sub­pop­u­la­tions.
    – Visuo-vestibu­lar and spino-vestibu­lar inter­ac­tions; cir­cuits and pro­cess­ing.
  • Theme 3 : vestibu­lar, ocu­lo­mo­tor & motor patholo­gies
    – Motor and locomotor con­trol in humans & ani­mal mod­els.
    – Cel­lu­lar deter­mi­nants of vestibu­lar diseases & motion sick­ness.
    – Mouse mod­el of vestibular disease, Myelin-relat­ed diseases & idio­path­ic nys­tag­mus.
Available positions
  • Postdoctoral position: Exploring the neural basis of multisensory control of head direction activity

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Selected publications
  • Ante­ri­or thal­a­m­ic exci­ta­tion and feed-for­ward inhi­bi­tion of pre­subic­u­lar neu­rons pro­ject­ing to medi­al entorhi­nal cor­tex. Nas­sar M, et al., Frick­er D : J Neu­rosci, 2018
  • No Gain No Pain: Rela­tions Between Vestibu­lo-Ocu­lar Reflex­es and Motion Sick­ness in Mice. Idoux E, Tagli­abue M, Bera­neck M : Front Neu­rol, 2018
  • Activ­i­ty depen­dent feed­back inhi­bi­tion may main­tain head direc­tion sig­nals in mouse pre­subicu­lum. Simon­net J, et al., Frick­er D : Nat Com­mun, 2017

  • The visu­al encod­ing of pure­ly pro­pri­o­cep­tive inter­man­u­al tasks is due to the need of trans­form­ing joint sig­nals, not to their inter­hemi­spher­ic trans­fer. Arnoux L, et al., Tagli­abue M : J Neu­ro­phys­i­ol,2017
  • Long-Last­ing Visuo-Vestibu­lar Mis­match in Freely-Behav­ing Mice. Car­caud et al., Bera­neck M : ENeu­ro, 2017

 

TEAM MEMBERS

Permanent researchers

Mathieu BERANECK

Mathieu BERANECK

CR CNRS

Team leader

David DUBAYLE

David DUBAYLE

MCF

Desdemona FRICKER

Desdemona FRICKER

CR CNRS

Team leader

Marc MAIER

Marc MAIER

PR U.Paris Diderot

David MALINVAUD

David MALINVAUD

MCU-PH

Joe MCINTYRE

Joe MCINTYRE

DR CNRS

Michele TAGLIABUE

Michele TAGLIABUE

IR

Post docs and PhD students

Filipa BARROS

Filipa BARROS

PhD student

Louis RICHEVAUX

Louis RICHEVAUX

PhD student

Louise SCHENBERG

Louise SCHENBERG

PhD student

François SIMON

François SIMON

PhD student

PUBLICATIONS ▼

Articles

Chapters

Speech communication

Patent

SPATIAL ORIENTATION GROUP

The team is working on spa­tial ori­en­ta­tion, a sys­tem-lev­el top­ic, by study­ing its under­ly­ing func­tion­al and struc­tur­al deter­mi­nants in ani­mals, as well as by ana­lyz­ing human behav­ior on earth and in space. We rely on a wide range of exper­i­men­tal approach­es, and we care­ful­ly tie togeth­er dif­fer­ent lev­els of inves­ti­ga­tion in an over­arch­ing frame­work. This mul­ti-lay­ered approach and com­bi­na­tion of exper­tise ded­i­cat­ed to func­tion­al stud­ies con­sti­tute the team’s uniqueness at both the nation­al and inter­na­tion­al lev­el.
Basic under­stand­ing gained in exper­i­ments per­formed both on ground and in weight­less­ness will be applied to bet­ter diag­nose and treat dis­eases, and con­verse­ly, patho­log­i­cal dys­func­tion may allow new insight into healthy brain func­tion.
Our work is sup­port­ed by the French spa­tial agency (CNES), ANR, CNRS & Uni­ver­sité Paris Descartes.

RESEARCH TOPICS ▼

Theme 1 : Mul­ti­sen­so­ry inte­gra­tion, Ori­en­ta­tion and Spa­tial Per­cep­tion
– Visuo-hap­tic inte­gra­tion and spa­tial per­cep­tion.
– Visuo-vestibu­lar inter­ac­tions for spa­tial ori­en­ta­tion.
– Influ­ence of grav­i­ty on mul­ti­sen­so­ry inte­gra­tion: weight­less­ness and hyper­grav­i­ty exper­i­ments.
Theme 2 : Cor­ti­cal and sub­cor­ti­cal cir­cuits for spa­tial ori­en­ta­tion
– Role of inhi­bi­tion in the thal­a­mo-pre­subic­u­lar pro­cess­ing of head direc­tion sig­nals.
– Head direc­tion cir­cuit archi­tec­ture and spe­cif­ic role of neu­ronal sub­pop­u­la­tions.
– Visuo-vestibu­lar and spino-vestibu­lar inter­ac­tions; cir­cuits and pro­cess­ing.
Theme 3 : vestibu­lar, ocu­lo­mo­tor & motor patholo­gies
– Motor and locomotor con­trol in humans & ani­mal mod­els.
– Cel­lu­lar deter­mi­nants of vestibu­lar diseases & motion sick­ness.
– Mouse mod­el of vestibular disease, Myelin-relat­ed diseases & idio­path­ic nys­tag­mus.

SELECTED PUBLICATIONS ▼

 Ante­ri­or thal­a­m­ic exci­ta­tion and feed-for­ward inhi­bi­tion of pre­subic­u­lar neu­rons pro­ject­ing to medi­al entorhi­nal cor­tex. Nas­sar M, et al., Frick­er D : J Neu­rosci, 2018
No Gain No Pain: Rela­tions Between Vestibu­lo-Ocu­lar Reflex­es and Motion Sick­ness in Mice. Idoux E, Tagli­abue M, Bera­neck M : Front Neu­rol, 2018
– Activ­i­ty depen­dent feed­back inhi­bi­tion may main­tain head direc­tion sig­nals in mouse pre­subicu­lum. Simon­net J, et al., Frick­er D : Nat Com­mun, 2017
– The visu­al encod­ing of pure­ly pro­pri­o­cep­tive inter­man­u­al tasks is due to the need of trans­form­ing joint sig­nals, not to their inter­hemi­spher­ic trans­fer. Arnoux L, et al., Tagli­abue M : J Neu­ro­phys­i­ol,2017
– Long-Last­ing Visuo-Vestibu­lar Mis­match in Freely-Behav­ing Mice. Car­caud et al., Bera­neck M : ENeu­ro, 2017

TEAM MEMBERS

Permanent researchers

Mathieu BERANECK

Mathieu BERANECK

CR CNRS

Team leader

David DUBAYLE

David DUBAYLE

MCF

Desdemona FRICKER

Desdemona FRICKER

CR CNRS

Team leader

Marc MAIER

Marc MAIER

PR U.Paris Diderot

David MALINVAUD

David MALINVAUD

MCU-PH

Joe MCINTYRE

Joe MCINTYRE

DR CNRS

Michele TAGLIABUE

Michele TAGLIABUE

IR

Post docs & PhD students

Filipa BARROS

Filipa BARROS

PhD student

Louis RICHEVAUX

Louis RICHEVAUX

PhD student

Louise SCHENBERG

Louise SCHENBERG

PhD student

François SIMON

François SIMON

PhD student

PUBLICATIONS ▼

Articles

Chapters

Speech communication

Patent