GLIA-GLIA AND GLIA-NEURON INTERACTIONS GROUP

Our group is interested in understanding the role of glial cells in the mammalian central nervous system and the mechanisms by which glial cells and neurons interact to support normal communication in the CNS. We try to understand the role of glial cells in the mammalian central (CNS) and peripheral nervous systems (PNS), and the mechanisms by which glial cells and neurons interact to support normal sensory processing and perception. We are developing and using a set of interdisciplinary and complementary tools (electrophysiology, chemogenetics, 2-photon Ca2+ imaging, immunohistochemistry, biochemistry, and behavior) and approaches to selectively manipulate and monitor glial cell signaling and investigate its effects in synaptic transmission, plasticity, and memory underlying sensory processing. From these studies, we hope to resolve some glial cell functions, and open up entirely new areas of investigation and potential treatments of diseases. Indeed, astrocytes play a major role in many neurological disorders, and it has become clear that sensory perception, notably visual perception, touch and proprioception, are impaired in some of them.

Research topics
  • THEME 1: Roles of astrocyte and satellite glial cell signaling in synaptic transmission, plasticity, memory and sensory processing
  • THEME 2: Roles of astrocyte signaling and satellite glial cells in neuroinflammation: implications for neurodevelopmental (schizophrenia and autism) and neurodegenerative (Alzheimer’s disease, Parkinson’s disease, Friedreich’s ataxia) disorders
  • THEME 3: Astrocytic – microglia interactions
Meeting organization
  • 2020 : Création du CAV (Club Autisme, troubles neurodéveloppementaux et Vision)

  • Fête de la Science 2020: Conférence en ligne “Autisme et vision”  🌐

  • Premières rencontres du CAV (Club Autisme, troubles neurodéveloppementaux et Vision) – Janvier 2021   🌐
  • Deuxièmes rencontres du CAV (Club Autisme, troubles neurodéveloppementaux et Vision) – Juin 2021   🌐
  • Troisièmes rencontres du CAV (Club Autisme, troubles neurodéveloppementaux et Vision) – Septembre 2021   🌐
  • Fête de la Science 2021: Conférence en ligne “Autisme et perception des émotions”  🌐
  • Quatrièmes rencontres du CAV (Club Autisme, troubles neurodéveloppementaux et Vision) – Novembre 2021 🌐

TEAM MEMBERS

Permanent researchers

Cendra AGULHON

Cendra AGULHON

CR, HDR CNRS

Team leader Deputy director of the Center

Marie PIERON

Marie PIERON

IR CNRS

Jacques STINNAKRE

Jacques STINNAKRE

DR CNRS

Consultant

Visiting scientists

Nicholas PRIEBE

Nicholas PRIEBE

Invited Pr U.Texas USA

Support staff

Sophie GUINOISEAU

Sophie GUINOISEAU

Assistant Engineer

Post docs, PhD and Master students

Pauline MERIAU

Pauline MERIAU

PhD student

Elsie MOUKARZEL

Elsie MOUKARZEL

PhD student

Teaching assistant (ATER)

Valentin RITOU

Valentin RITOU

PhD student

Aarushi JUYAL

Aarushi JUYAL

Erasmus, M1 student

Trimitie GODREAU

Trimitie GODREAU

Intern

Julia WENG

Julia WENG

Intern

︾ SELECTED PUBLICATIONS ︾

Articles

GLIA-GLIA AND GLIA-NEURON INTERACTIONS GROUP

Our group is interested in understanding the role of glial cells in the mammalian central nervous system and the mechanisms by which glial cells and neurons interact to support normal communication in the CNS. We try to understand the role of glial cells in the mammalian central (CNS) and peripheral nervous systems (PNS), and the mechanisms by which glial cells and neurons interact to support normal sensory processing and perception. We are developing and using a set of interdisciplinary and complementary tools (electrophysiology, chemogenetics, 2-photon Ca2+ imaging, immunohistochemistry, biochemistry, and behavior) and approaches to selectively manipulate and monitor glial cell signaling and investigate its effects in synaptic transmission, plasticity, and memory underlying sensory processing. From these studies, we hope to resolve some glial cell functions, and open up entirely new areas of investigation and potential treatments of diseases. Indeed, astrocytes play a major role in many neurological disorders, and it has become clear that sensory perception, notably visual perception, touch and proprioception, are impaired in some of them.

RESEARCH TOPICS ︾

Theme 1: Roles of astrocyte and satellite glial cell signaling in synaptic transmission, plasticity, memory and sensory processing

Theme 2: Roles of astrocyte signaling and satellite glial cells in neuroinflammation: implications for neurodevelopmental (schizophrenia and autism) and neurodegenerative (Alzheimer’s disease, Parkinson’s disease, Friedreich’s ataxia) disorders

Theme 3: Astrocytic – microglia interactions

MEETING ORGANIZATION ︾
  • Fête de la Science 2020: Conférence en ligne “Autisme et vision”  🌐

  • Premières rencontres du CAV (Club Autisme, troubles neurodéveloppementaux et Vision) - Janvier 2021   🌐

  • 2020 : Création du CAV (Club Autisme, troubles neurodéveloppementaux et Vision)

  • Fête de la Science 2020: Conférence en ligne “Autisme et vision”  🌐

  • Premières rencontres du CAV (Club Autisme, troubles neurodéveloppementaux et Vision) – Janvier 2021   🌐
  • Deuxièmes rencontres du CAV (Club Autisme, troubles neurodéveloppementaux et Vision) – Juin 2021   🌐
  • Troisièmes rencontres du CAV (Club Autisme, troubles neurodéveloppementaux et Vision) – Septembre 2021   🌐
  • Fête de la Science 2021: Conférence en ligne “Autisme et perception des émotions”  🌐
  • Quatrièmes rencontres du CAV (Club Autisme, troubles neurodéveloppementaux et Vision) – Novembre 2021 🌐

    TEAM MEMBERS

    Permanent researchers

    Cendra AGULHON

    Cendra AGULHON

    CR CNRS, HDR

    Team leader, Deputy director of the Center

    Marie PIERON

    Marie PIERON

    IR CNRS

    Jacques STINNAKRE

    Jacques STINNAKRE

    DR CNRS, Consultant

    Visiting scientists

    Nicholas PRIEBE

    Nicholas PRIEBE

    Invited PR U.Texas USA

    Support staff

    Sophie GUINOISEAU

    Sophie GUINOISEAU

    Assistant Engineer

    Post docs, PhD & Master students

    Pauline MERIAU

    Pauline MERIAU

    PhD student

    Elsie MOUKARZEL

    Elsie MOUKARZEL

    PhD student, Teaching assistant (ATER)

    Valentin RITOU

    Valentin RITOU

    PhD student

    Aarushi JUYAL

    Aarushi JUYAL

    Erasmus, M1 student

    Trimitie GODREAU

    Trimitie GODREAU

    Intern

    Julia WENG

    Julia WENG

    Intern

    PUBLICATIONS ︾

    Articles