by Sophie Guinoiseau | Nov 16, 2022
Reconstructing rodent and human Neuronal Networks to model Neurodegenerative syndromes Summary Human brain is a complex organ composed of several hundred billions of cells and even more numerous interconnected cellular interactions. There is a high demand for...
by Sophie Guinoiseau | Oct 12, 2022
Summary The timescale dynamics of epilepsies: from seconds to decades Continuous long-term recordings (months to years) in patients with epilepsy directly show that seizures are regulated not only in a circadian manner, but also on a much slower time scale (days to...
by Sophie Guinoiseau | Sep 28, 2022
Summary The developmental history of the molecular synaptic code controlling excitatory connectivity The mature brain results from the formation of precise networks between functionally and morphologically distinct types of neurons. A given neuron forms synapses with...
by Sophie Guinoiseau | Sep 2, 2022
Summary Upon infection, bacterial compounds, and the pro-inflammatory cytokines they elicit, induce a complex response coordinated by the brain and known as “sickness behavior”. This response induces stereotyped behavioral changes (reduced locomotion and food intake,...
by Sophie Guinoiseau | Sep 2, 2022
Summary Addiction to cocaine: How you take the drug is more decisive than how much A widely used preclinical procedure to study features of cocaine addiction involves allowing laboratory animals to take drug continuously, for hours each day. However, data in human...