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Excitatory synapse regulators and their potential as therapeutic targets in chronic conditions by Jenny Gunnersen

by Sophie Guinoiseau | Jan 30, 2023

Excitatory synapse regulators and their potential as therapeutic targets in chronic conditions Summary  In this presentation, I will describe our recent work on a family of proteins with important roles in excitatory synapse development and maintenance. These proteins...

Genetic and environmental animal models of autism reproduce the spectrum of the disease, by Mohamed JABER

by Sophie Guinoiseau | Jan 23, 2023

Genetic and environmental animal models of autism reproduce the spectrum of the disease Summary  Genetic and environmental factors increase autism spectrum disorder (ASD) incidence and this has led to the generation of corresponding animal models, with some showing...

Disruption of the CoQ10 biosynthetic Complex Q causes mitochondrial dysfunction and Ca2+ imbalance in Purkinje neurons in COQ8A-ataxia, by Helene Puccio

by Sophie Guinoiseau | Nov 21, 2022

 Disruption of the CoQ10 biosynthetic Complex Q causes mitochondrial dysfunction and Ca2+ imbalance in Purkinje neurons in COQ8A-ataxia Summary COQ8A-Ataxia is a rare form of neurodegenerative disorder due to mutations in the COQ8A gene. The encoded mitochondrial...

Reconstructing rodent and human Neuronal Networks to model Neurodegenerative syndromes, by Jean-Michel Peyrin

by Sophie Guinoiseau | Nov 16, 2022

Reconstructing rodent and human Neuronal Networks to model Neurodegenerative syndromes Summary  Human brain is a complex organ composed of several hundred billions of cells and even more numerous interconnected cellular interactions. There is a high demand for...

The timescale dynamics of epilepsies: from seconds to decades, by Christophe Bernard

by Sophie Guinoiseau | Oct 12, 2022

Summary The timescale dynamics of epilepsies: from seconds to decades Continuous long-term recordings (months to years) in patients with epilepsy directly show that seizures are regulated not only in a circadian manner, but also on a much slower time scale (days to...
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