A Satellite Event of the FENS Forum 2022

Friday July the 8th

Registration is Free but mandatory

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SE11 NEUROSCIENCES IN SPACE

This satellite meeting is dedicated to neuroscience experiments conducted in collaboration with space agencies to follow astronauts brain health and mental performance. Space flight creates particular living conditions that cause isolation, a drastic reduction of physical activity, an important exposure to radiation and a long-lasting reduction of gravity. The combination of these environmental alterations induces the so-called “space fog”, i.e the perturbation of the astronauts’ capacities to accurately perceive its environment and efficiently interact with it. Many experiments concerning proprioception, sensory, motor and cognitive functions are carried out by astronauts during their flights to evaluate the effects on the brain of this challenging environment. In addition to spaceflights, studies conducted during parabolic flights, bed-rest and dry immersion will be reported to explore the link between gravity sensing and brain functions, but also the effects of social isolation and sedentariness. We will finally discuss how animal experiments allow understanding the cellular and molecular basis of brain adaptation to real or simulated space-flight conditions.

Cady Coleman inserting conductive gel to the EEG-capturing scalp of the Neurospat experiment. The Neurospat is a study of spatial cognition, novelty processing and sensorimotor integration, composed of two principal experimental tasks: visual orientation and visuomotor tracking, plus additional, standardized electroencephalogram (EEG) tasks performed as a means of assessing general effects of the space station environment on EEG signals. ©ESA/NASA

Organizers

Mathieu Beraneck & Michele Taglabue (INCC – UMR 8002 CNRS – Université Paris Cité)
Lionel Bringoux (ISM – UMR 7287 CNRS – Aix Marseille Université)
Jean-Luc Morel, Etienne Guillaud, Didier Le Ray (INCIA – UMR 5287 CNRS – Université de Bordeaux)
Pierre Denise & Gilles Clément (COMETE – UMRS1075 Inserm – Université de Caen Normandie).

List of speakers

Program 08/07/2022

9h

Welcome.

9h15 – 9h25

Introduction by Mathieu Beraneck.

9h30 – 10h30

Plenary lecture by Gilles Clément; chairman Pierre Denise

10h30 – 12h

Session 1 Sensory-motor functions; chairman Michele Tagliabue

– Joe McIntyre: the role of gravity in eye-hand coordination
– Lionel Bringoux: Initial state estimates of gravity-related force field shape motor control of goal-directed movements
– Philippe Lefèvre: Dexterous Manipulation in Microgravity (GRIP project)
– Ana Maria Cebolla Alvarez: EEG brain oscillations during a free-floating visuo-motor task in weightlessness

12h – 13h15

Lunch break

13h15 – 15h

Session 2 Structural and cognitive plasticity; chairman Lionel Bringoux

– Heather McGregor: Impacts of Spaceflight Experience on Human Brain Structure
– Friedl-Werner Anika: Hippocampal plasticity in response to spaceflight; the effects of isolation, confinement, and inactivity
– Raffaella Ricci: Effects of microgravity on cognitive functions during parabolic flights
– Pierre Denise: Intracranial pressure during parabolic flight, dry immersion and head down tilt bed rest
– Floris Wuyts: Perivascular spaces are differently affected by microgravity in NASA astronauts than in Roscosmos cosmonauts. A solution for SANS?

15h – 15h30

Coffee break

15h30 – 17h

Session 3 Cellular and Molecular basis of brain adaptation; chairman Didier Le Ray

– Isabelle Mackrous: Neural evidence of an internal model of gravity
– Jérôme Carriot: Neural adaptation to a new sensory environment
– Alexandra Gros: alteration of adult neurogenesis in hindlimb suspended rats. Effect of exercise countermeasure
– Philippe De Deurwaerdère: alteration of adult neurogenesis in hindlimb suspended rats. Effect of exercise countermeasure

16h30 – 17h

Panel discussion: Spationauts engaged in neuroscience experiments; Chairwoman Alexandra Gros, Guillemette Gauquelin-Koch, Jean-Luc Morel

Angelique Van Ombergen Directorate of Human Spaceflight and Robotic Exploration Programmes (to be confirmed)

17h15 – 18h

Good-bye cocktail

Location : 45 rue des St-Pères

Access to the Satellite will be restricted to participants with confirmed registration

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