Neurophysiological substrates for gaze stabilization during passive movement and locomotion, by Mathieu Beraneck

Abstract Neurophysiological substrates for gaze stabilization during passive movement and locomotion

All vertebrates share the need to stabilize the visual field during motion with rapid counteracting eye adjustments. Gaze control largely results from the sensory-motor transformation which primarily depends on the integration of visual and vestibular inputs. The optokinetic and vestibulo-ocular reflex are known to both contribute to gaze stabilization during passive, externally applied movements. During active movement however, sensory-motor pathways are supplemented by other neural signals.

During this talk, I will first illustrate the differential organization of central vestibular pathways by focusing on the subpopulations of neurons responsible for visuo-vestibular integration and implicated in the vestibulo-ocular reflex (VOR) pathway and its adaptation. I will then present data that demonstrate in both xenopus and mice that during locomotion, an efferent copy signal originating from spinal-CPG participates early on to gaze control.

Short Biography

Mathieu Beraneck is a senior CNRS researcher (DR position pending). He is co-leader of the Spatial Orientation team, at INCC (CNRS-Université de Paris). M. Beraneck was trained as an in vitro and in vivo electrophysiologist. He is the author of about 40 publications and a recognized expert in the vestibular field. He has been and is principal investigator on several ANR Projects. He is participating to the UFR activities as a member of the ethical committee, scientific council, and was recently appointed as “responsable de la structure du bien-être animal”. He is also managing teaching activities within the BME and Neurosciences Masters.

To join the ZOOM meeting

https://u-paris.zoom.us/j/86330641281?pwd=d00yZS8wUVZuaEJmQlN0d1YwQWZtUT09

ID of the meeting : 863 3064 1281

Code : 256542